This includes integrated consideration of room air change rates, fume hood exhaust alternatives, and fume hood sash management.

In the Labs21 Design Guide, see the following topics:
- Room air change rates
- Impact of fume hood diversity and face velocity
- Glove boxes and biological safety cabinets as alternatives to fume hoods
- Mini environments to reduce laboratory ventilation load
- Sash management training

Also see these related codes and standards:
- California code on fume hood face velocity
- Ventilation standards from ACGIH, OSHA and ANSI


See these Labs21 Conference Presentations for more information on the following topics:
- Use of CFD modeling to optimize room air change rates in a university laboratory (phone forum presentation)
- Use of CFD modeling to optimize room air change rates in a pharmaceutical laboratory.

These Labs21 Case Studies implement this strategy:
- Fred Hutchinson Cancer Research Center changed min air change rate from 10 ACH to 6 ACH (occupied) and 4 ACH (unoccupied). (pg. 5, 6)
- The Georgia Public Health laboratory changed from 10 ACH to 6 ACH for BSL-2 labs (pg. 6)
- The Whitehead Building reduced vivarium air change rates by using ventilated cages (pg.5)
- The Labs21 Energy Analysis Study has data on the energy impact of different ventilation rates (section 2.1)

See the Frequently Asked Questions (FAQ) list